(1-Butylpiperidin-4-yl)methyl 1H-indole-7-carboxylate - Names and Identifiers
(1-Butylpiperidin-4-yl)methyl 1H-indole-7-carboxylate - Physico-chemical Properties
(1-Butylpiperidin-4-yl)methyl 1H-indole-7-carboxylate - Introduction
1H-Indole-7-carboxylic acid, (1-butyl-4-piperidinyl)methyl ester is an organic compound with the chemical formula C19H27NO2. The following is a description of its nature, use, preparation and safety information:
Nature:
1H-Indole-7-carboxylic acid, (1-butyl-4-piperidinyl)methyl ester is a colorless or yellowish liquid. It has a special smell and volatilizes at room temperature. It has a relatively low density, and its melting and boiling points are about -20 ° C and 221 ° C, respectively.
Use:
1H-Indole-7-carboxylic acid, (1-butyl-4-piperidinyl)methyl ester is an important organic synthesis intermediate. It is commonly used in the medical field as a precursor for the preparation of drugs and biologically active molecules. In addition, in some chemical reactions, it can also be used as a catalyst and solvent.
Method:
A common synthesis method is to react indole and 1-butyl-4-piperidinemethanol under acidic conditions, and then react with Formic Anhydride to obtain the product. The reaction is carried out by an esterification reaction, and the synthesis can be carried out under appropriate temperature and reaction conditions.
Safety Information:
1H-Indole-7-carboxylic acid, (1-butyl-4-piperidinyl)methyl ester should pay attention to the following safety precautions during use and storage:
1. Because of its volatility, it should be used in a well-ventilated place and avoid prolonged contact;
2. Avoid inhaling its vapor and pay attention to protective equipment to avoid contact with skin and eyes;
3. In the operation to be careful protection, avoid violent shaking, to prevent splashing around;
4. If inhaled by mistake or skin contact occurs, please wash immediately and seek medical help;
5. Store it in a sealed container, away from fire and oxidizing agents to avoid fire or explosion.
Last Update:2024-04-09 21:04:16